An Increase in Fat-Free Mass is Associated with Higher Appetite and Energy Intake in Older Adults: A Randomised Control Trial

Cross-sectional studies in younger adults have demonstrated a positive association between energy intake (EI) and fat-free mass (FFM), with this relationship seemingly mediated by resting metabolic rate (RMR). Establishing causal effect longitudinally would be prudent older suffering from loss of appetite. We investigated the effects FFM on RMR, appetite EI 39 healthy (age: 66 ± 4 years, BMI: 25.1 3.5 kg?m2) assigned to either 12-week resistance training + protein supplementation group (RT PRO) or control (CON). Body composition, subjective appetite, leptin, insulin, RMR laboratory-measured ad libitum were measured at baseline, weeks 6 12 intervention, while daily baseline week 12. (+1.2 kg; p = 0.002), postprandial (+8 mm; 0.027), (+119 kcal; 0.012) (+133 0.010) increased RT PRO. fasted leptin insulin concentrations remained unchanged (all > 0.05). The increases correlated (r 0.527, 0.001), 54% change attributed changes. In conclusion, associated an adults.